About 8 results found for searched term "52-01-7" (0.117 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2423 | AZD7545 | PDK1 |
| AZD7545 is a potent PDHK inhibitor with IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2, respectively. | ||
| M3028 | Spironolactone | Mineralocorticoid Receptor |
| SC9420; Abbolactone | ||
| Spironolactone (SC9420) is an oral active aldosterone mineralocorticoid receptor antagonist with an IC50 value of 24 nM. Spironolactone is also an androgen receptor antagonist with an IC50 of 77 nM. Spironolactone promotes podocyte autophagy. | ||
| M4373 | Gypenoside-A | Others |
| Gypenoside-A is a natural product isolated from Gynostemma pentaphyllum, has anti-cancer, hypoglycemic, hypolipidemic, immune enhancement effects, etc. | ||
| M5415 | Amphotericin B | Antibiotic |
| NSC 527017 | ||
| Amphotericin B (AmB) is an amphipathic polyene antibiotic which permeabilizes ergosterol-containing membranes. | ||
| M28797 | BMS-8 | PD-1/PD-L1 |
| BMS-8 inhibits the PD-1/PD-L1 interaction with IC50 of 7.2 μM. BMS-8, binds directly to PD-L1 and induces formation of PD-L1 homodimers, which in turn prevents the interaction with PD-1. | ||
| M29690 | SK-575-NEG | PARP |
| SK-575-NEG (compound 28), a methylation counterpart of SK-575, is synthesized by methylation of the amino group of piperidine-2,6-dione in SK-575 as an control compound. SK-575-NEG is strongly bound to PARP1, with an IC50 of 2.64 nM. SK-575-NEG was completely ineffective in inducing PARP1 degradation in MDA-MB-436 and Capan-1 cells at concentrations up to 1 μM. | ||
| M52534 | Z-Leu-Leu-Leu-AMC | Proteasome |
| Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome. | ||
| M54141 | PAR-4 Agonist Peptide, amide | PAR |
| PAR-4 Agonist Peptide, amide (PAR-4-AP; AY-NH2) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist. | ||
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