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 About 1 result found for searched term "4311-88-0" (0.123 seconds)

Cat.No.  Name Target
M2315 Necrostatin-1 RIPK
Nec-1
Necrostatin-1 (NEC-1) is a potent inhibitor of necroptosis, with an EC50 of 490 nM in Jurkat cells. Necrostin-1 is the first identified RIPK1 inhibitor, EC50=182 nM, that reduces inflammation and inhibits colitis associated tumorigenesis. Necrostatin-1 (Nec-1) is also an inhibitor of IDO.



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