Free shipping on all orders over $ 500

Zerumbone

Cat. No. M8868
Zerumbone Structure
Size Price Availability
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Zerumbone is a TRAIL-induced apoptosis potentiator. It potentiates TRAIL-induced apoptosis through the up-regulation of DR4 and DR5 expression and the down-regulation of cFLIP. Zerumbone has very little or no cytotoxic effect on the normal human endothelial cells and dermal fibroblasts. Zerumbone is a sesquiterpene isolated from in Zingiber zerumbet Smith (wild ginger).

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 218.33
Formula C15H22O
CAS Number 471-05-6
Purity >98%
Solubility DMSO: ≥10 mg/mL
Storage at -20°C
Related Products
AX-024 hydrochloride

AX-024 hydrochloride is a potent cytokine release inhibitor, inhibits the production of interferon-γ (IFN-γ), interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), IL-10 and IL-17A.

Chlorin E6

Chlorin E6 is a natural molecule and a promising photosensitizer, isolated from renewable natural sources.

Calf thymus DNA

Calf thymus DNA is high quality double-stranded template DNA isolated from the thymus of male and female calves.

PEG300

PEG300 is a neutral and biocompatible hydrophilic polymer.

MnTMPyP Pentachloride

MnTMPyP Pentachloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Zerumbone supplier, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.