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Z-VAD(OH)-FMK

Cat. No. M6231
Z-VAD(OH)-FMK Structure
Size Price Availability Quantity
5mg USD 375 In stock
10mg USD 675 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Z-VAD(OH)-FMK is the non-methylated form of Z-VAD-FMK, and useful in studies including recombinant, or purified enzymes.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 453.46
Formula C21H28FN3O7
CAS Number 161401-82-7
Purity >98%
Solubility 90 mg/mL in DMSO
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Z-VAD(OH)-FMK supplier, Caspase, inhibitors

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