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Xylazine HCl

Cat. No. M6060
Xylazine HCl Structure
Size Price Availability Quantity
100mg USD 50 In stock
500mg USD 100 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Xylazine is an α2-Adrenergic receptor agonist, used as a sedative and muscle relaxant.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 256.79
Formula C12H16N2S.HCl
CAS Number 23076-35-9
Purity >99%
Solubility 50 mg/mL in DMSO
Storage at -20°C
References

Effects of medetomidine and xylazine on intraocular pressure and pupil size in healthy Beagle dogs.
Kanda T, et al. Vet Anaesth Analg. 2015 Nov;42(6):623-8. PMID: 25704794.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Xylazine HCl supplier, Adrenergic Receptor, inhibitors

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