X80 is an inhibitor of xeroderma pigmentosum group A protein (XPA protein) required for the removal of all types of DNA lesions repaired by nucleotide excision repair Including both transcription coupled and global genomic nucleotide excision repair.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Solubility||DMSO: ≥40 mg/mL|
AX-024 hydrochloride is a potent cytokine release inhibitor, inhibits the production of interferon-γ (IFN-γ), interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), IL-10 and IL-17A.
Chlorin E6 is a natural molecule and a promising photosensitizer, isolated from renewable natural sources.
|Calf thymus DNA
Calf thymus DNA is high quality double-stranded template DNA isolated from the thymus of male and female calves.
PEG300 is a neutral and biocompatible hydrophilic polymer.
MnTMPyP Pentachloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger.
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