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Vinpocetine

Cat. No. M6054
Vinpocetine Structure
Synonym:

RGH-4405

Size Price Availability Quantity
100mg USD 80 In stock
200mg USD 120 In stock
500mg USD 280 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Vinpocetine is a selective inhibitor of voltage-sensitive sodium channel for the treatment of stroke, vascular dementia and Alzheimer's disease.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 350.45
Formula C22H26N2O2
CAS Number 42971-09-5
Purity >99%
Solubility 3 mg/mL warmed in DMSO
Storage at -20°C
References

Vinpocetine modulates metabolic activity and function during retinal ischemia.
Nivison-Smith L, et al. Am J Physiol Cell Physiol. 2015 May 1;308(9):C737-49. PMID: 25696811.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Vinpocetine, RGH-4405 supplier, Sodium Channel, inhibitors

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