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Vidarabine

Cat. No. M6053
Vidarabine Structure
Size Price Availability Quantity
100mg USD 60 In stock
200mg USD 90 In stock
500mg USD 135 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Vidarabine is an antiviral drug by interfering with the synthesis of viral DNA, used to treat herpes simplex and varicella zoster viruses.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 267.24
Formula C10H13N5O4
CAS Number 5536-17-4
Purity >99%
Solubility 53 mg/mL in DMSO
Storage at -20°C
References

Vidarabine is neither a potent nor a selective AC5 inhibitor.
Seifert R, et al. Biochem Pharmacol. 2014 Feb 15;87(4):543-6. PMID: 24398424.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Vidarabine supplier, DNA/RNA Synthesis, inhibitors

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