Free shipping on all orders over $ 500

UDP-Gal

Cat. No. M10051
UDP-Gal Structure
Size Price Availability Quantity
50mg USD 688  USD688 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

UDP-Gal is a nucleotide sugar. UDP-Gal can block BALB/3T12 cell development. UDP-Gal has been used as a component in galactosyltransferase labeling buffer to prelabel terminal N-acetylglucosamine (GlcNAc) on immunoglobulin chains. It has also been used as a component in Hyp O-galactosyltransferase (HPGT) assay.

Chemical Information
Molecular Weight 566.3
Formula C15H24N2O17P2
CAS Number 2956-16-3
Solubility (25°C) Water 45 mg/mL
Storage -20°C, dry, sealed, protect from light
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Shinya Fushinobu. Curr Opin Chem Biol. Molecular evolution and functional divergence of UDP-hexose 4-epimerases

[2] Yuzhou Fan, et al. Biotechnol Bioeng. Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation

[3] Yang Zou, et al. Carbohydr Res. One-pot three-enzyme synthesis of UDP-Glc, UDP-Gal, and their derivatives

[4] Jennifer M I Daenzer, et al. PLoS Genet. UDP-galactose 4'-epimerase activities toward UDP-Gal and UDP-GalNAc play different roles in the development of Drosophila melanogaster

[5] Dorota Maszczak-Seneczko, et al. Acta Biochim Pol. Subcellular localization of UDP-GlcNAc, UDP-Gal and SLC35B4 transporters

Related Metabolite/Endogenous Metabolite Products
Biliverdin

Biliverdin is the product of the oxidation of bilirubin. Biliverdin can be synthesized via a non-protoporphyrin pathway in Corynebacterium glutamicum.

Stachyose hydrate

Stachyose tetrahydrate is a functional oligosaccharide, acts as a prebiotic. Stachyose tetrahydrate can prevent indirectly colon cancer cell growth by promoting the proliferation of probiotics or producing beneficial materials in the intestine. Stachyose hydrate exhibit a hypoglycemic effect, and improve inflammation through modulating gut microbiota.

Stachyose tetrahydrate

Stachyose tetrahydrate is a functional oligosaccharide, acts as a prebiotic. Stachyose tetrahydrate can prevent indirectly colon cancer cell growth by promoting the proliferation of probiotics or producing beneficial materials in the intestine.

1-Methylxanthine

1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.

Mannan

Mannan is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  Catalog
Abmole Inhibitor Catalog




Keywords: UDP-Gal supplier, Metabolite/Endogenous Metabolite, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.