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Triflupromazine is a member of a class of drugs called phenthiazines, which are dopamine D1/D2 receptor antagonists.
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
| Molecular Weight | 388.88 |
| Formula | C18H20ClF3N2S |
| CAS Number | 1098-60-8 |
| Purity | >99% |
| Solubility | DMSO |
| Storage | at -20°C |
| Related Dopamine Receptor Products |
|---|
| SHP099 hydrochloride
SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM. |
| Sulpiride
Sulpiride is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. |
| rac-Rotigotine (Hydrochloride)
rac-Rotigotine Hcl is a high potency and selectivity agonist for D-2 receptor with Ki of 0.69 nM. |
| Promazine HCl
Promazine (hydrochloride) is a D2 dopamine receptor antagonist, belongs to the phenothiazine class of antipsychotics, used to treat schizophrenia. |
| Prochlorperazine dimaleate salt
Prochlorperazine dimaleate is a dopamine (D2) receptor antagonist. |
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