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Triacetin

Cat. No. M6029
Triacetin Structure
Synonym:

Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane

Size Price Availability Quantity
100mg USD 60 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Triacetin is a triglyceride that is used as an antifungal agent.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 218.20
Formula C9H14O6
CAS Number 102-76-1
Purity >99%
Solubility 10 mM in DMSO
Storage at -20°C
References

Intra-gastric triacetin alters upper gastrointestinal motility in conscious dogs.
Oosaka K, et al. World J Gastroenterol. 2014 Jan 28;20(4):1054-60. PMID: 24574778.

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Keywords: Triacetin, Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane supplier, inhibitors

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