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trans-Cinnamic acid

Cat. No. M11465
trans-Cinnamic acid Structure
Synonym:

trans-Cinnamic acid; Phenylacrylic acid, Cinnamylic acid

Size Price Availability Quantity
100mg USD 50  USD50 In stock
200mg USD 70  USD70 In stock
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Quality Control & Documentation
Biological Activity

Trans-cinnamic acid was A fungicide with A minimum inhibitory concentration (MIC) of 250 μg/mL against A. sobria (SY-AS1).

Chemical Information
Molecular Weight 148.16
Formula C9H8O2
CAS Number 140-10-3
Form Solid
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage 2-8°C
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Fernanda Lima Torres de Aquino, et al. J Tissue Viability. trans-Cinnamic acid, but not p-coumaric acid or methyl cinnamate, induces fibroblast migration through PKA- and p38-MAPK signalling pathways

[2] Rodrigo da Silva Viana, et al. Nat Prod Res. Effect of trans-cinnamic acid and p-coumaric acid on fibroblast motility: a pilot comparative study of in silico lipophilicity measure

[3] Nancy E Dvila-Guzmn, et al. ACS Omega. Microwave-Assisted Synthesis of trans-Cinnamic Acid for Highly Efficient Removal of Copper from Aqueous Solution

[4] Jasmina Kurepa, et al. Commun Integr Biol. trans-Cinnamic acid-induced leaf expansion involves an auxin-independent component

[5] Nam Hyeon Kang, et al. Nutrients. Trans-Cinnamic Acid Stimulates White Fat Browning and Activates Brown Adipocytes

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Keywords: trans-Cinnamic acid, trans-Cinnamic acid; Phenylacrylic acid, Cinnamylic acid supplier, Antibiotic, inhibitors, activators


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