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Tranexamic Acid

Cat. No. M6024
Tranexamic Acid Structure
Size Price Availability Quantity
100mg USD 50 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 157.21
Formula C8H15NO2
CAS Number 1197-18-8
Purity >98%
Solubility 100 mg/mL in water
Storage at -20°C
References

The current place of tranexamic acid in the management of bleeding.
Hunt BJ, et al. Anaesthesia. 2015 Jan;70 Suppl 1. PMID: 25440395.

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  Catalog
Abmole Inhibitor Catalog 2017




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