Free shipping on all orders over $ 500

Toluidine Blue

Cat. No. M10062
Toluidine Blue Structure
Size Price Availability Quantity
500mg USD 50  USD50 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
  • Purity: Biological Stain
  • COA
  • MSDS
Biological Activity

Toluidine Blue is a photosensitizer gel, which can make the medicine stay on the diseased part and improve the treatment effect. Toluidine blue is a nucleic acid-prone eosinophilic dye that stays in tissues with more nuclear components. It has a good penetration depth in the tissue, and can be effectively distributed in the infected target tissue.

Chemical Information
Molecular Weight 373.97
Formula C15H16ClN3S.1/2(ZnCl2)
CAS Number 6586-04-5
Storage RT, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Guanyu Su, et al. Transl Vis Sci Technol. Evaluation of Toluidine Blue-Mediated Photodynamic Therapy for Experimental Bacterial Keratitis in Rabbits

[2] Alper Keten, et al. Am J Emerg Med. Toluidine blue

[3] Ekkehard Hewer, et al. Acta Cytol. Ultrafast Toluidine Blue Staining for Rapid On-Site Evaluation of Cytological Smears

[4] G P Wysocki. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. Toluidine blue--viewpoints

[5] H Ephros, et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. Toluidine blue--viewpoints

Related Fluorescent Dye Products
FM1-43

FM1-43 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM1-43 is widely used in endocytic and exospic membrane structure markers.

BCIP

BCIP is a chromogenic substrate for colorimetric assay of alkaline phosphatase activity.

MCA-SEVNLDAEFR-K(Dnp)-RR, amide

MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate.

MeOSuc-AAPV-AMC

MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm).

Enhanced Green Fluorescent Protein (EGFP) (200-208)

Enhanced Green Fluorescent Protein (EGFP) (200-208) is a marker gene product derived from the jellyfish Aequorea Victoria.

  Catalog
Abmole Inhibitor Catalog




Keywords: Toluidine Blue supplier, Fluorescent Dye, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.