Free shipping on all orders over $ 500


Cat. No. M6023
Tolnaftate Structure
Size Price Availability Quantity
100mg USD 60 In stock
Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 307.41
Formula C19H17NOS
CAS Number 2398-96-1
Purity >99%
Solubility 10 mM in DMSO
Storage at -20°C

Study of tolnaftate release from fatty acids containing ointment and penetration into human skin ex vivo.
Kezutyte T, et al. Acta Pol Pharm. 2011 Nov-Dec;68(6):965-73. PMID: 22125963.

Related Products
Glutaminase C-IN-1

Glutaminase C-IN-1 (968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts.


NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of ~50 μM in a cell-free assay; does not inhibit the closely related targets, Cdc42 or RhoA.


Budesonide is a GC steroid commonly used for the treatment of asthma and non-infectious rhinitis.


Brequinar is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.


Laropiprant is a potent, selective DP1 receptor antagonist with Ki value of 0.57 nM, and exhibits > 1,000 fold selectivity over DP2 receptor (Ki=0.75 μM).

Abmole Inhibitor Catalog 2017

Keywords: Tolnaftate supplier, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.