Free shipping on all orders over $ 500


Cat. No. M11517
TMA-DPH Structure
Size Price Availability
1mg USD 98  USD98 Out of stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Tma-dph contains a cationic trimethylammonium substitute that can be used as a surface anchor locator to improve the localization of the fluorescent probe DPH in the membrane. The maximum excitation/emission wavelength is 355nm/430nm, and it is blue fluorescent and stored at room temperature away from light.

*The compound is unstable in solutions, freshly prepared is recommended

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 461.62
Formula C28H31NO3S
CAS Number 115534-33-3
Purity >98%
Solubility N/A
Storage -20°C , protect from light , dry , sealed

[1] Antnio M T M do Canto, et al. Biochim Biophys Acta. Diphenylhexatriene membrane probes DPH and TMA-DPH: A comparative molecular dynamics simulation study

[2] Brad Chazotte. Cold Spring Harb Protoc. Labeling the plasma membrane with TMA-DPH

[3] C Saldanha, et al. J Membr Biol. Fluorescent probes DPH, TMA-DPH and C17-HC induce erythrocyte exovesiculation

[4] G Ferretti, et al. Membr Biochem. Properties of a phosphatidylcholine derivative of diphenyl hexatriene (DPH-PC) in lymphocyte membranes. A comparison with DPH and the cationic derivative TMA-DPH using static and dynamic fluorescence

[5] A Benedetti, et al. J Gastroenterol Hepatol. Plasma membrane fluidity in isolated rat hepatocytes: comparative study using DPH and TMA-DPH as fluorescent probes

Related Fluorescent Dye Products
Rose Bengal

Rose Bengal is a red or rose color dye and is anionic in nature. It is a 4,5,6,7-tetrachloro 2′,4′,5′,7′-tetraiodo derivative of fluorescein. It is widely used to detect damage to the ocular surface epithelium in ocular surface diseases such as dry eye and herpetic keratitis. Rose Bengal has mild antiviral potency. Rose Bengal is used to stain dead and degenerating cells and mucus.

Fluo-8 AM

Fluo-8 AM is a calcium fluorescent probe that can be loaded into protoplasts to detect calcium in apple flesh cells. The maximum excitation/emission wavelength is 495nm/516nm, which needs to be stored under -15℃ under light protection.

Z-Gly-Gly-Arg-AMC acetate

Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

Thioflavine S

Thioflavine S is a fluorescent histochemical marker of dense core senile plaques.

Thiazole Orange

Thiazole orange is an unsymmetrical cyanine dye which can be conjugated to oligonucleotides (ONs) to create fluorogenic hybridisation probes. Thiazole orange can be used for reticulocyte analysis.

Abmole Inhibitor Catalog

Keywords: TMA-DPH supplier, Fluorescent Dye, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.