Free shipping on all orders over $ 500

Tildipirosin

Cat. No. M6134
Tildipirosin Structure
Size Price Availability Quantity
5mg USD 350 In stock
10mg USD 500 In stock
50mg USD 1500 In stock
Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Results indicated that metaphylactic administration of tildipirosin to calves 5 days prior to H somni challenge prevented subsequent culture of the pathogen from bronchial secretions and was more effective in minimizing clinical disease and lung lesions than was metaphylactic administration of tulathromycin.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 734.02
Formula C41H71N3O8
CAS Number 328898-40-4
Purity >99%
Solubility 10 mM in DMSO
Storage at -20°C
References

Clinical disease and lung lesions in calves experimentally inoculated with Histophilus somni five days after metaphylactic administration of tildipirosin or tulathromycin.
Confer AW, et al. Am J Vet Res. 2016 Apr;77(4):358-66. PMID: 27027834.

Visualizing the 16-membered ring macrolides tildipirosin and tilmicosin bound to their ribosomal site.
Poehlsgaard J, et al. ACS Chem Biol. 2012 Aug 17;7(8):1351-5. PMID: 22563863.

Related Products
Propofol

Propofol inhibited tumor size, cell viability and promoted cell apoptosis via inhibiting mTOR/p70S6K pathway mediated by HOTAIR in cervical cancer.

Propacetamol Hydrochloride

Propacetamol is water soluble and can be directly injected.

Cetilistat

Cetilistat is an inhibitor of pancreatic and gastrointestinal lipases. It has great treatment of obesity in both diabetic and non-diabetic patients.

Calcium-Sensing Receptor Antagonists I

Calcium-Sensing Receptor Antagonists I is an antagonist of calcium-sensing parathyroid hormone receptors.

AS101

AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Tildipirosin supplier, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.