Free shipping on all orders over $ 500

Thymidine

Cat. No. M8964
Thymidine Structure
Synonym:

DThyd; Deoxyribothymidine; NSC 21548

Size Price Availability Quantity
25mg USD 45  USD45 In stock
50mg USD 60  USD60 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Thymidine is a pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose.

Product Citations
Chemical Information
Molecular Weight 242.23
Formula C10H14N2O5
CAS Number 50-89-5
Solubility (25°C) Water 40 mg/mL
DMSO ≥ 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Takashi Osawa, et al. Synthesis and properties of oligonucleotides bearing thymidine derivatives with 1,6-dioxaspiro[4.5]decane skeleton

[2] Huabing Sun, et al. Independent Generation and Reactivity of Thymidine Radical Cations

[3] Werner Tjarks, et al. Carboranyl thymidine analogues for neutron capture therapy

[4] Bjrn Spilsberg, et al. Thymidine secretion by hybridoma and myeloma cells

[5] R Spector. Thymidine transport in the central nervous system

Related DNA/RNA Synthesis Products
DTP3 TFA

DTP3 TFA is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor.

Mating Factor α (1-6)

Mating Factor α (1-6) is a mating factor produced by α-mating type cells of Saccharomyces cerevisiae and an acts as an inhibitor of the initiation of DNA synthesis in the cells.

Polynucleotide kinase

Polynucleotide Kinase is a DNA repair enzyme.

Tetrapeptide

Tetrapeptide, an analogue of α-MSH, induces melanin synthesis.

Branaplam hydrochloride

Branaplam hydrochloride is an orally active, brain-permeable, selective modulator of SMN2 splicing, with an EC50 of 20 nM for SMN, and enhances full-length SMN protein and prolongs survival in a mouse model of severe spinal muscular atrophy (SMA). Branaplam hydrochloride also inhibits hERG with an IC50 of 6.3 μM.

  Catalog
Abmole Inhibitor Catalog




Keywords: Thymidine, DThyd; Deoxyribothymidine; NSC 21548 supplier, DNA/RNA Synthesis, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.