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Taxifolin

Cat. No. M4585
Taxifolin Structure
Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
20mg USD 50 In stock
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Quality Control
Biological Activity

Taxifolin, type I inhibitor for VEGFR-2 kinase, is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 304.25
Formula C15H12O7
CAS Number 480-18-2
Purity 99.58%
Solubility 61 mg/mL in DMSO
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




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