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Tamsulosin

Cat. No. M5988
Tamsulosin Structure
Size Price Availability Quantity
10mg USD 60 In stock
50mg USD 150 In stock
100mg USD 250 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Tamsulosin is a selective α1 receptor antagonist.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 408.51
Formula C20H28N2O5S
CAS Number 106133-20-4
Purity >99%
Solubility 51.9 mg/mL in DMSO
Storage at -20°C
References

Tamsulosin combined with solifenacin versus tamsulosin monotherapy for male lower urinary tract symptoms: a meta-analysis.
Gong M, et al. Curr Med Res Opin. 2015;31(9):1781-92. PMID: 26211817.

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  Catalog
Abmole Inhibitor Catalog 2017




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