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Sulpiride

Cat. No. M5984
Sulpiride Structure
Synonym:

Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil

Size Price Availability Quantity
100mg USD 70 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Sulpiride is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 341.43
Formula C15H23N3O4S
CAS Number 15676-16-1
Purity >99%
Solubility 68 mg/mL in DMSO
Storage at -20°C
References

Detecting potential adverse reactions of sulpiride in schizophrenic patients by prescription sequence symmetry analysis.
Lai EC, et al. PLoS One. 2014 Feb 27;9(2):e89795. PMID: 24587038.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Sulpiride, Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil supplier, Dopamine Receptor, inhibitors

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