Free shipping on all orders over $ 500

Sulpiride

Cat. No. M5984
Sulpiride Structure
Synonym:

Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil

Size Price Availability Quantity
100mg USD 65 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Sulpiride is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 341.43
Formula C15H23N3O4S
CAS Number 15676-16-1
Purity >98%
Solubility 68 mg/mL in DMSO
Storage at -20°C
References

Detecting potential adverse reactions of sulpiride in schizophrenic patients by prescription sequence symmetry analysis.
Lai EC, et al. PLoS One. 2014 Feb 27;9(2):e89795. PMID: 24587038.

Related Dopamine Receptor Products
SHP099 hydrochloride

SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM.

rac-Rotigotine (Hydrochloride)

rac-Rotigotine Hcl is a high potency and selectivity agonist for D-2 receptor with Ki of 0.69 nM.

Promazine HCl

Promazine (hydrochloride) is a D2 dopamine receptor antagonist, belongs to the phenothiazine class of antipsychotics, used to treat schizophrenia.

Prochlorperazine dimaleate salt

Prochlorperazine dimaleate is a dopamine (D2) receptor antagonist.

Pramipexole dihydrochloride

Pramipexole 2Hcl is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Sulpiride, Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil supplier, Dopamine Receptor, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.