Sucrose can be used to make citric acid, caramel, invert sugar, transparent soap and so on. Sucrose can inhibit bacterial growth in high concentration, and can be used as preservative and antioxidant excipient in medicine.
| Molecular Weight | 342.3 |
| Formula | C12H22O11 |
| CAS Number | 57-50-1 |
| Solubility (25°C) | Water 500 mg/mL |
| Storage | RT, dry, sealed |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
[1] Joachim Dissemond, et al. Sucrose octasulfate-evidence in the treatment of chronic wounds
[2] William Craig Stagner, et al. Sucrose octaacetate
[3] No authors listed. Cold Spring Harb Protoc. Sucrose Cutting Solution
[4] David Daud, et al. Sucrose analogs: an attractive (bio)source for glycodiversification
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