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Rifampicin

Cat. No. M5930
Rifampicin Structure
Synonym:

Rimactane

Size Price Availability Quantity
100mg USD 70 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Rifampin is a DNA-dependent RNA polymerase inhibitor, used to treat a number of bacterial infections.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 822.94
Formula C43H58N4O12
CAS Number 13292-46-1
Purity >99%
Solubility 100 mg/mL in DMSO
Storage at -20°C
References

Formulation of novel sustained release rifampicin-loaded solid lipid microparticles based on structured lipid matrices from Moringa oleifera.
Onyishi IV, et al. Pharm Dev Technol. 2015;20(5):546-54. PMID: 24964095.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Rifampicin, Rimactane supplier, DNA/RNA Synthesis, inhibitors

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