Free shipping on all orders over $ 500

Promazine HCl

Cat. No. M5903
Promazine HCl Structure
Size Price Availability Quantity
50mg USD 70 In stock
Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Promazine (hydrochloride) is a D2 dopamine receptor antagonist, belongs to the phenothiazine class of antipsychotics, used to treat schizophrenia.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 320.88
Formula C17H21ClN2S
CAS Number 53-60-1
Purity >99%
Solubility 48 mg/mL in water
Storage at -20°C
References

Exanthema medicamentosum as a side effect of promazine.
Lasić D, et al. Psychiatr Danub. 2011 Jun;23(2):194-7. PMID: 21685860.

Related Dopamine Receptor Products
Sulpiride

Sulpiride is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.

rac-Rotigotine (Hydrochloride)

rac-Rotigotine Hcl is a high potency and selectivity agonist for D-2 receptor with Ki of 0.69 nM.

Prochlorperazine dimaleate salt

Prochlorperazine dimaleate is a dopamine (D2) receptor antagonist.

Pramipexole dihydrochloride

Pramipexole 2Hcl is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.

Perphenazine

Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Promazine HCl supplier, Dopamine Receptor, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.