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Procainamide hydrochloride

Cat. No. M3358
Procainamide hydrochloride Structure
Synonym:

Procainamide HCl

Size Price Availability Quantity
50mg USD 70 In stock
100mg USD 80 In stock
1g USD 200 In stock
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Biological Activity

Procainamide hydrochloride is a sodium channel blocker, and also a DNA methyltransferase inhibitor. Procainamide HCl is used in the treatment of cardiac arrhythmias.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 271.79
Formula C13H22ClN3O
CAS Number 614-39-1
Purity >99%
Solubility DMSO
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Procainamide hydrochloride, Procainamide HCl supplier, Sodium Channel, inhibitors

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