Potassium bicarbonate is an important chemical raw material, mainly used to produce potassium carbonate, potassium acetate, potassium arsenite, etc., and also used in medicine, food, fire extinguishing agent and other industries.
| Molecular Weight | 100.12 |
| Formula | KHCO3 |
| CAS Number | 298-14-6 |
| Solubility (25°C) | Water ≥ 200 mg/mL |
| Storage | RT, dry, sealed |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
[3] Tara T T Tran, et al. Review of Evidence for Adult Diabetic Ketoacidosis Management Protocols
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