Free shipping on all orders over $ 500


Cat. No. M9756
Pocapavir Structure

SCH-48973; V-073

Size Price Availability Quantity
10mg USD 140 In stock
25mg USD 280 In stock
100mg USD 900 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Pocapavir (also known as SCH-48973 and V-073) is a potent, selective anti-enterovirus agent. Pocapavir inhibited 80% of 154 recent human enterovirus isolates at an IC50 of 0.9 microg/ml. The affinity constant (Ki) for SCH-48973 binding to poliovirus was 8.85x10-8 M. SCH-48973 demonstrated efficacy in a murine poliovirus model of enterovirus disease. SCH-48973 represents a potential candidate for therapeutic intervention against enterovirus infections.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 423.72
Formula C21H17Cl3O3
CAS Number 146949-21-5
Purity >99%
Solubility DMSO ≥ 90 mg/mL
Storage at -20°C

Neonatal Enterovirus Myocarditis With Severe Dystrophic Calcification: Novel Treatment With Pocapavir
Samuel G Wittekind, et al. J Investig Med High Impact Case Rep. 2017 Sep 14;5(3):2324709617729393. PMID: 28944227.

Antiviral Activity of Pocapavir in a Randomized, Blinded, Placebo-Controlled Human Oral Poliovirus Vaccine Challenge Model
Marc S Collett, et al. J Infect Dis. 2017 Feb 1;215(3):335-343. PMID: 27932608.

Related Anti-infection Products
8-Epidiosbulbin E acetate

8-Epidiosbulbin E acetate is abundant in Dioscorea bulbifera L. , it exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria.


Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABACls) and l-glutamate-gated chloride channels (GluCls).


CHIR-090 is a very potent and selective LpxC inhibitor, it is also a two-step slow, tight-binding inhibitor of E. coli LpxC with Ki = 4.0 nM.


Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes.


Qstatin is a selective inhibitor of quorum sensing (QS) in vibrio species.

Abmole Inhibitor Catalog 2017

Keywords: Pocapavir, SCH-48973; V-073 supplier, Anti-infection, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.