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PIK-293

Cat. No. M3450
PIK-293 Structure
Size Price Availability
5mg USD 140 Custom Synthesis
10mg USD 260 Custom Synthesis
50mg USD 780 Custom Synthesis
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

PIK-293 is a PI3-K inhibitor. PIK-293 inhibit the p110α, p110β, p110δ, and p110γ with IC50 of 100uM,25μM,0.24μM,and 10μM.PIK-293 is the parent compand of PIK-294.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 397.43
Formula C22H19N7O
CAS Number 900185-01-5
Purity >98%
Solubility DMSO 70 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: PIK-293 supplier, PI3K, inhibitors

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