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Phloretin

Cat. No. M4607
Phloretin Structure
Synonym:

NSC 407292; RJC 02792

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
200mg USD 42 In stock
500mg USD 62 In stock
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Quality Control
Biological Activity

Phloretin is a dihydrochalcone found in apple tree leaves, which shows beneficial effects on diabetes.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 274.27
Formula C15H14O5
CAS Number 60-82-2
Purity >99%
Solubility 35 mg/mL in DMSO
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Phloretin, NSC 407292; RJC 02792 supplier, SGLT, inhibitors

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