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PEG300

Cat. No. M9292
PEG300 Structure
Synonym:

PEG-300; Polyethylene glycol

Size Price Availability Quantity
100g USD 50 In stock
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Quality Control
Biological Activity

PEG300 is a neutral and biocompatible hydrophilic polymer. PEG-300 is usually used to modify therapeutic proteins and peptides to increase their solubility.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 104.15
Formula C5H12O2
CAS Number 25322-68-3
Purity
Solubility DMSO ≥ 60 mg/mL
Water ≥ 45 mg/mL
Storage 2-8°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: PEG300, PEG-300; Polyethylene glycol supplier, inhibitors

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