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Panaxydol

Cat. No. M9964
Panaxydol Structure
Size Price Availability Quantity
5mg USD 370  USD370 In stock
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Quality Control & Documentation
Biological Activity

Panaxydol has significant anti-inflammatory, anti-platelet aggregation, inhibition of cell oxidase, inhibition of leukemia cell growth, and inhibition of thrombosis.

Chemical Information
Molecular Weight 260.37
Formula C17H24O2
CAS Number 72800-72-7
Storage 2-8°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Hee Suk Kim, et al. Int J Cancer. Panaxydol, a component of Panax ginseng, induces apoptosis in cancer cells through EGFR activation and ER stress and inhibits tumor growth in mouse models

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