(-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Solubility||64 mg/mL in DMSO|
|Related Phosphatase Products|
TPI-1 is a SHP-1 inhibitor, inhibits recombinant SHP-1 with an IC50 of 40 nM.
RMC-4550 is a potent and selective SHP2 inhibitor, with an IC50 of 0.583 nM.
|β-Glycerol phosphate disodium salt pentahydrate
β-Glycerol phosphate disodium salt pentahydrate is a potent protein phosphatase and tensin homolog (PTEN) inhibitor.
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM.
Okadaic acid is a potent inhibitor of protein phosphatase 1/2A with IC50 values of 19 nM and 0.2 nM for protein phosphatase 1 and protein phosphatase 2A, respectively.
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