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Oxytocin (Syntocinon)

Cat. No. M5845
Oxytocin (Syntocinon) Structure
Synonym:

α-Hypophamine; Oxytocic hormone

Size Price Availability Quantity
5mg USD 65 In stock
10mg USD 115 In stock
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Biological Activity

Oxytocin (α-Hypophamine) is a mammalian neurohypophysial hormone; its actions are mediated by specific, high-affinity oxytocin receptors; ligand of oxytocin receptor.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 1007.19
Formula C43H66N12O12S2
CAS Number 50-56-6
Purity 98.69%
Solubility 10 mM in DMSO
Storage at -20°C
References

Intranasal oxytocin in the treatment of autism spectrum disorders: a review of literature and early safety and efficacy data in youth.
Anagnostou E, et al. Brain Res. 2014 Sep 11;1580:188-98. PMID: 24508578.

Related Oxytocin Receptor Products
Carbetocin

Carbetocin is an agonist at peripheral oxytocin receptors.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Oxytocin (Syntocinon), α-Hypophamine; Oxytocic hormone supplier, Oxytocin Receptor, inhibitors

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