Olive oil is an oil extracted from the olives (Olea europaea). The health benefits of olive oil result from its higher proportion of monounsaturated fats, as well as its antioxidant constituents: hydroxytyrosol, oleuropein and oleocanthal.
Slightly soluble in ethanol (95%); miscible with ether, chloroform, light petroleum (50–70°C), and carbon disulfide.
Oxid Med Cell Longev. 2022 Apr 16;2022:4505513.
Nrf2-Mediated Ferroptosis Inhibition Exerts a Protective Effect on Acute-on-Chronic Liver Failure
Olive oil purchased from AbMole
| CAS Number | 8001-25-0 |
| Solubility (25°C) | miscible with ether and chloroform and carbon disulfide |
| Storage | 2-8°C, protect from light, sealed |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
[2] Antonio Maria Borz, et al. Nutrients. Olive Oil Effects on Colorectal Cancer
[4] Cristina Angeloni, et al. Int J Mol Sci. Bioactivity of Olive Oil Phenols in Neuroprotection
[5] Luca Fernndez del Ro, et al. Molecules. Olive Oil and the Hallmarks of Aging
| Related Solvents & Excipients Products |
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| ATX-002
ATX-002 is an ionizable cationic lipid for RNA drug delivery with theoretical pKa (c-pKa) and measured pKa values of 8.68 and 6.03, respectively. |
| 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE is a phospholipid that can be used in studies related to drug delivery. |
| PEG1500
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| PLGA lactide:glycolide (50:50) (MW 90000)
PLGA lactide:glycolide (50:50) (MW 90000) Poly(D,L-propylidene-CO-ethylidene glycolide) is a synthetic amino acid that can be used for macromolecular delivery. |
Products are for research use only. Not for human use. We do not sell to patients.
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