Neticonazole Hydrochloride is an imidazole antifungal for the treatment of fungal skin infections. Neticonazole is reported as a potent exosome inhibitor which can block the activity of exosomes.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Solubility||DMSO: ≥ 50 mg/mL|
High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer.
Datta A, et al. Sci Rep. 2018 May 25;8(1):8161. PMID: 29802284.
|Related Anti-infection Products|
Cefquinome sulfate is a broad-spectrum fourth-generation cephalosporin antibiotic.
Cefathiamidine is the first generation of cephalosporin antibacterial used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis.
Nifuratel is a local antiprotozoal and antifungal agent used in gynecology.
Piroctone Olamine is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff, fungal infections.
Triadimenol (Triademenol) is a triazole-type fungicide that was identified as weak estrogen receptor agonists, Triademenol is reported as a potent exosome inhibitor which can block the activity of exosomes.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.