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Naphazoline HCl

Cat. No. M5808
Naphazoline HCl Structure
Size Price Availability Quantity
100mg USD 50 In stock
500mg USD 70 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 246.74
Formula C14H15ClN2
CAS Number 550-99-2
Purity >99%
Solubility 10 mM in DMSO
Storage at -20°C
References

Determination of naphazoline hydrochloride in biological and pharmaceutical samples by a quantum dot-assisted chemiluminescence system using response-surface methodology.
Imani-Nabiyyi A, et al. Luminescence. 2014 Dec;29(8):994-1002. PMID: 24733642.

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  Catalog
Abmole Inhibitor Catalog 2017




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