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Mesterolone

Cat. No. M3685

Mesterolone Structure
Size Price Availability Quantity
50mg USD 180 In stock
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Biological Activity

Mesterolone significantly increased pectoralis mass and fiber size. All SC indices and number of myonuclei increased significantly by mesterolone administration. Mesterolone can induce avian skeletal muscle hypertrophy and that this is correlated with increased number of SCs.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 304.47
Formula C20H32O2
CAS Number 1424-00-6
Purity >99%
Solubility DMSO
Storage at -20°C
References

Influence of mesterolone on satellite cell distribution and fiber morphology within maturing chicken pectoralis muscle.
Allouh MZ, et al. Anat Rec (Hoboken). 2012 May;295(5):792-9. PMID: 22419647.

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