Mesterolone significantly increased pectoralis mass and fiber size. All SC indices and number of myonuclei increased significantly by mesterolone administration. Mesterolone can induce avian skeletal muscle hypertrophy and that this is correlated with increased number of SCs.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
Influence of mesterolone on satellite cell distribution and fiber morphology within maturing chicken pectoralis muscle.
Allouh MZ, et al. Anat Rec (Hoboken). 2012 May;295(5):792-9. PMID: 22419647.
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