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Malathion

Cat. No. M5760
Malathion Structure
Size Price Availability Quantity
10mg USD 80 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Malathion is an organophosphate parasympathomimetic which binds irreversibly to cholinesterase, is an insecticide of relatively low human toxicity.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 330.36
Formula C10H19O6PS2
CAS Number 121-75-5
Purity >99%
Solubility 3.8 mg/mL in DMSO
Storage at -20°C
References

Preparation of malathion MIP-SPE and its application in environmental analysis.
Zuo HG, et al. Environ Monit Assess. 2015 Jul;187(7):394. PMID: 26038320.

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  Catalog
Abmole Inhibitor Catalog 2017




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