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Lisinopril

Cat. No. M5747
Lisinopril Structure
Size Price Availability Quantity
50mg USD 68 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Lisinopril is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 405.49
Formula C21H31N3O5
CAS Number 76547-98-3
Purity >99%
Solubility 10 mM in DMSO
Storage at -20°C
References

Hypertension in hemodialysis patients treated with atenolol or lisinopril: a randomized controlled trial.
Agarwal R, et al. Nephrol Dial Transplant. 2014 Mar;29(3):672-81. PMID: 24398888.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Lisinopril supplier, ACE, inhibitors

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