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Cat. No. M5723
Lacidipine Structure


Size Price Availability Quantity
10mg USD 70 In stock
50mg USD 270 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Lacidipine is a L-type calcium channel blocker, used for treating high blood pressure.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 455.54
Formula C26H33NO6
CAS Number 103890-78-4
Purity >99%
Solubility 91 mg/mL in DMSO
Storage at -20°C

Lacidipine attenuates TNF-α-induced cardiomyocyte apoptosis.
Wang QL, et al. Cytokine. 2015 Jan;71(1):60-5. PMID: 25226445.

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Abmole Inhibitor Catalog 2017

Keywords: Lacidipine, GX-1048,GR-43659X,SN-305 supplier, Calcium Channel, inhibitors

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