Free shipping on all orders over $ 500

KPT-276

Cat. No. M2795
KPT-276 Structure
Size Price Availability
50mg USD 220 Out of stock
Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

KPT-276 is an orally bioavailable selective CRM1 inhibitor.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 426.26
Formula C16H10F8N4O
CAS Number 1421919-75-6
Purity >99%
Solubility DMSO 10 mg/mL
Storage at -20°C
Related CRM1 Products
KPT-330

KPT-330 is an orally bioavailable selective CRM1 inhibitor.

KPT-185

KPT-185 is a selective CRM1 inhibitor.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: KPT-276 supplier, CRM1, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.