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Kinetin

Cat. No. M2793
Kinetin Structure
Synonym:

6-Furfurylaminopurine

Size Price Availability Quantity
10mM*1mL in DMSO USD 32  USD32 In stock
5g USD 30  USD30 In stock
10g USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Kinetin is a kind of cytokinin, a class of plant hormone that promotes cell division.

Chemical Information
Molecular Weight 215.21
Formula C10H9N5O
CAS Number 525-79-1
Solubility (25°C) DMSO 35 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Michal Mielcarek, et al. Kinetin stimulates differentiation of C2C12 myoblasts

[2] M Masroor A Khan, et al. Nanotized kinetin enhances essential oil yield and active constituents of mint via improvement in physiological attributes

[3] Barbara Makov, et al. Cytoprotective activities of kinetin purine isosteres

[4] Alena Kadlecov, et al. The plant hormone kinetin in disease therapy and healthy aging

[5] Jan Barciszewski, et al. Kinetin--a multiactive molecule

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