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Iproniazid phosphate

Cat. No. M5710

Iproniazid phosphate  Structure
Size Price Availability Quantity
100mg USD 60 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Iproniazid is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 277.21
Formula C9H16N3O5P
CAS Number 305-33-9
Purity >99%
Solubility 10 mM in DMSO
Storage at -20°C
References

Human anti-mitochondria autoantibodies appearing in iproniazid-induced immunoallergic hepatitis recognize human liver monoamine oxidase B.
Pons C, et al. Biochem Biophys Res Commun. 1996 Jan 5;218(1):118-24. PMID: 8573115.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Iproniazid phosphate supplier, Monoamine Oxidase, inhibitors

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