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Indole-3-acetamide

Cat. No. M9230
Indole-3-acetamide Structure
Synonym:

3-Indolylacetamide; NSC 1969

Size Price Availability Quantity
2g USD 150 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Indole-3-acetamide is an auxin precursor. Indole-3-acetamide was used in the synthesis of [5.5.6.6]diazafenestrane skeleton and indole-3-acetic acid.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 174.20
Formula C10H10N2O
CAS Number 879-37-8
Purity >98%
Solubility
Storage 2-8°C, dry, sealed
References

Total syntheses of leuconoxine, leuconodine B, and melodinine E by oxidative cyclic aminal formation and diastereoselective ring-closing metathesis.
Umehara A, et al. Org Lett. 2014 May 2;16(9):2526-9. PMID: 24754345.

Indole-3-acetic acid in plant-microbe interactions.
Duca D, et al. Antonie Van Leeuwenhoek. 2014 Jul;106(1):85-125. PMID: 24445491.

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Keywords: Indole-3-acetamide, 3-Indolylacetamide; NSC 1969 supplier, inhibitors

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