Free shipping on all orders over $ 500

ICG-OSu

Cat. No. M21459
ICG-OSu Structure
Synonym:

ICG NHS ester

Size Price Availability Quantity
5mg USD 450  USD450 In stock
10mg USD 700  USD700 In stock
25mg USD 1350  USD1350 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

ICG-OSu (ICG NHS ester) is a near infrared fluorescent agent with amine reactivity that is widely used in the design of in vivo imaging probes. Em >750 nm infrared, Ex >750 nm infrared.

Chemical Information
Molecular Weight 828.04
Formula C49H53N3O7S
CAS Number 1622335-40-3
Solubility (25°C) DMSO : 25 mg/mL
Storage -20℃, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Elvira Garca de Jaln, et al. Mol Imaging Biol. Comparison of Five Near-Infrared Fluorescent Folate Conjugates in an Ovarian Cancer Model

[2] Ying Zhou, et al. Bioconjug Chem. A Novel Near-Infrared Fluorescent Probe TMTP1-PEG4-ICG for in Vivo Tumor Imaging

Related Fluorescent Dye Products
FM1-43

FM1-43 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM1-43 is widely used in endocytic and exospic membrane structure markers.

BCIP

BCIP is a chromogenic substrate for colorimetric assay of alkaline phosphatase activity.

MCA-SEVNLDAEFR-K(Dnp)-RR, amide

MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate.

MeOSuc-AAPV-AMC

MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm).

Enhanced Green Fluorescent Protein (EGFP) (200-208)

Enhanced Green Fluorescent Protein (EGFP) (200-208) is a marker gene product derived from the jellyfish Aequorea Victoria.

  Catalog
Abmole Inhibitor Catalog




Keywords: ICG-OSu, ICG NHS ester supplier, Fluorescent Dye, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.