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Hexacosanoic acid

Cat. No. M9120
Hexacosanoic acid Structure
Synonym:

Ceratinic acid; Ceric acid

Size Price Availability Quantity
10mg USD 80  USD80 In stock
50mg USD 180  USD180 In stock
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Biological Activity

Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.

Chemical Information
Molecular Weight 396.69
Formula C26H52O2
CAS Number 506-46-7
Form Solid
Solubility (25°C) DMSO 10 mM
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Yamamoto Y, et al. J Nutr Sci Vitaminol (Tokyo). Chemical Synthesis of a Very Long-Chain Fatty Acid, Hexacosanoic Acid (C26:0), and the Ceramide Containing Hexacosanoic Acid.

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Keywords: Hexacosanoic acid, Ceratinic acid; Ceric acid supplier, Metabolite/Endogenous Metabolite, inhibitors, activators


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