Free shipping on all orders over $ 500

Glycyrrhizic acid

Cat. No. M3909
Glycyrrhizic acid Structure


Size Price Availability Quantity
10mg USD 50 In stock
50mg USD 100 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
Biological Activity

Glycyrrhizic acid shows anti-inflammatory, antiulcerous and antiallergic effects.glycyrrhizic acid may have potential as a therapeutic agent in cerebral ischemia by preventing oxidative stress. Glycyrrhizic acid would be a promising carrier for the oral delivery of PTX.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 822.94
Formula C42H62O16
CAS Number 1405-86-3
Purity 98.85%
Solubility DMSO 30mg/mL
Storage 2-8°C, dry, protect from light, sealed

Bioavailability Enhancement of Paclitaxel via a Novel Oral Drug Delivery System: Paclitaxel-Loaded Glycyrrhizic Acid Micelles.
Yang FH, et al. Molecules. 2015 Mar 6;20(3):4337-56. PMID: 25756651.

The Neuroprotective Effect of Glycyrrhizic Acid on an Experimental Model of Focal Cerebral Ischemia in Rats.
Akman T, et al. Inflammation. 2015 Feb 17. PMID: 25687639.

[Effects of buspirone complex with glycyrrhizic acid on behavior of mice with anxious-depressive state].
Fomina MK, et al. Ross Fiziol Zh Im I M Sechenova. 2014 Jul;100(7):808-19. PMID: 25669106.

Protective Effects of Glycyrrhizic Acid and 18β-Glycyrrhetinic Acid against Cisplatin-Induced Nephrotoxicity in BALB/c Mice.
Wu CH, et al. J Agric Food Chem. 2015 Jan 26. PMID: 25588318.

Related Dehydrogenase Products

Ivosidenib is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity.


BAY1436032 specifically inhibits R-2HG production and colony growth, and induces myeloid differentiation of AML cells.


Trilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing’s syndrome.


Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.


SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.

Abmole Inhibitor Catalog 2017

Keywords: Glycyrrhizic acid, Glycyrrhizin supplier, Dehydrogenase, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.