Glycerol is a clear, colourless, viscous, sweet-tasting liquid. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis.
Cell Res. 2023 Jun;33(6):464-478.
SCUBE2 mediates bone metastasis of luminal breast cancer by modulating immune-suppressive osteoblastic niches
Glycerol purchased from AbMole
Cancer Res Commun. 2022 Aug.
Pharmacological inhibition of SHP2 blocks both PI3K and MEK signaling in low-epiregulin HNSCC via GAB1
Glycerol purchased from AbMole
| Molecular Weight | 92.09 |
| Formula | C3H8O3 |
| CAS Number | 56-81-5 |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage | RT, protect from light, dry, sealed |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
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| Ammonium persulfate substitute
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| Avidin (from egg white)
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| Polyvinylpyrrolidone
Polyvinylpyrrolidone (PVP, Polyvidone, Povidone) is an inert, water-soluble, non-toxic, temperature-resistant, ph-stable, biocompatible, biodegradable polymer that helps encapsulate and meet the needs of hydrophilic and lipopphilic drugs. Polyvinylpyrrolidone has been widely tested and used as an effective wound healing promoter. |
| Acrylamide
Acrylamide is a neurotoxic monomer with a wide range of industrial uses. It is a precursor compound of polyacrylamide. |
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