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Ginsenoside-Rg2

Cat. No. M4067
Ginsenoside-Rg2 Structure
Synonym:

Chikusetsusaponin I; Panaxoside Rg2; Prosapogenin C2

Size Price Availability Quantity
5mg USD 60  USD60 In stock
10mg USD 100  USD100 In stock
20mg USD 150  USD150 In stock
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Quality Control & Documentation
Biological Activity

Ginsenoside-Rg2 is one of the major active components of ginseng, acts as a NF-κB inhibitor.

Chemical Information
Molecular Weight 785.01
Formula C42H72O13
CAS Number 52286-74-5
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Young-Suk Cho, et al. Korean J Physiol Pharmacol. Ginsenoside rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell

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Keywords: Ginsenoside-Rg2, Chikusetsusaponin I; Panaxoside Rg2; Prosapogenin C2 supplier, NF-κB, inhibitors, activators


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