Fluorescein dye is a common fluorescent probe. It is very high molar absorptivity at the wavelength of the argon laser (488 nm), large fluorescence quantum yield and high photostability makes it a very useful and sensitive fluorescent label.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Solubility||DMSO: ≥ 60 mg/mL|
|Storage||4°C, protect from light|
Absorption and fluorescence properties of fluorescein.
RobertSjoback, et al. Spectrochim Acta A Mol Biomol Spectrosc. 1995 Jun;Vol.51, Issue 6, Pages L7-L21.
Chymostatin is a chymotryptase-like serine proteases inhibitor, with Ki values of 9.36 and 13.1 nM for chymotrypsin and chymase, respectively.
|Carboxymethyl cellulose sodium
Carboxymethyl cellulose sodium is frequently used as viscous agent, paste and barrier agent.
Ceruletide is a biologically active decapeptide isolated from the skin of the Australian frog Hyla caerulea, acts as a cholecystokinin receptor agonist.
Gibberellic acid (Gibberellin) is a plant hormone stimulating plant growth and development.
25-Hydroxycholesterol (a metabolite of cholesterol) is a potent and selective suppressor of IgA production by B cells (EC50≈65 nM).
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